You can use these string in URL, Save downloads to folder, and Save As download properties. For example you can set Save downloads to folder property to
C:\!in\[host]\[path] to sort download into directories.

[Host]
host name from URL (for example www.microsoft.com)
[Host`]
host name where all "." are replaced with "`" (for example www`microsoft`com)
[Host_]
host name where all "." are replaced with "_" (for example www_microsoft_com)
[Path]
Path from URL
[Path`]
Path where all "/" are replaced with "`"
[Path_]
Path where all "/" are replaced with "_"
[Protocol]
protocol name (ftp,http)
[Ext]
filename extension in URL
[WeekDayS]
Abbreviated weekday name
[FullWeekDayS]
Full weekday name
[MonthS]
Abbreviated month
[FullMonthS]
Full month name
[Day]
Day of month as decimal number (1 - 31)
[Hour]
Hour in 24-hour format (0 - 23)
[Hour12]
Hour in 12-hour format (1 - 12)
[DayOfYear]
Day of year as decimal number (1 - 366)
[Month]
Month as decimal number (1 - 12)
[Minute]
Minute as decimal number (0 - 59)
[AmPm]
Current locale's A.M./P.M. indicator for 12-hour clock
[Second]
Second as decimal number (00 - 59)
[Week]
Week of year as decimal number, with Sunday as first day of week (0 - 51)
[Weekday]
Weekday as decimal number (0 - 6; Sunday is 0)
[WeekOfYear]
Week of year as decimal number, with Monday as first day of week (0 - 51)
[Year]
Year without century, as decimal number (00 - 99)
[Year4]
Year with century, as decimal number
[TZ]
Time-zone name or abbreviation; no characters if time zone is unknown